? Montelukast is a leukotriene (loo-koe-try-een) inhibitor. Leukotrienes are substances in the body that are associated with the inflammation and constriction of airway muscles and the accumulation of fluid in the lungs, all of which occur during an asthma attack.

? Montelukast is used to prevent asthma attacks. Montelukast is also used in the treatment of seasonal nasal allergies.

? Montelukast may also be used for purposes other than those listed in this medication guide.

? Take montelukast exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

? Montelukast is usually taken in the evening. Follow your doctor's instructions.

? Swallow the regular tablets with a glass of water.

? Chew the chewable tablets thoroughly before swallowing.

? The granules can be given either directly into the mouth or mixed with a spoonful of cold or room temperature applesauce, mashed carrots, rice, or ice cream. The packet should not be opened until ready to use. After opening the packet, the full dose must be administered within 15 minutes. Never store any mixed or unmixed granules for use after 15 minutes. The granules are not intended to be dissolved in liquid however, liquids may be taken after administration of the medication.

? Montelukast can be taken with or without food.

? Do not stop taking montelukast without first talking to your doctor. It may be some time before you begin to notice effects from this medication.

? Continue taking any other asthma medications, as directed by your doctor.

? Montelukast will not stop an asthma attack that has already begun. Keep another medication on hand to treat attacks.

? Seek medical attention if you notice that you require more than your usual or more than the maximum amount of any asthma medication in a 24-hour period. An increased need for medication could be an early sign of a serious asthma attack.

? If you experience any of the following serious side effects, stop taking montelukast and seek emergency medical attention or notify your doctor immediately:

? an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

? severe inflammation (pain and swelling) of the sinuses; or

? Other, less serious side effects may be more likely to occur. Continue to take montelukast and talk to your doctor if you experience

? Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Not for use in animals hypersensitive(allergic) to montelukast or similar medications.
The safety of using montelukast in pregnant or locating animals (female animals nursing their young) has not been determined.

? Before taking montelukast, tell your doctor if you are taking rifampin (Rimactane, Rifadin) or phenobarbital (Luminal, Solfoton). You may not be able to take montelukast, or you may require a dosage adjustment or special monitoring during your treatment.

? Drugs other than those listed here may also interact with montelukast. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

? Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take the next regularly scheduled dose as directed. Do not take a double dose of this medication.

? Store montelukast at room temperature away from moisture and heat.